

He became a member of a comedic group at the Comedy Workshop, known as the Texas Outlaw Comics, that also included Bill Hicks, Ron Shock, Riley Barber, Steve Epstein, Andy Huggins, John Farneti, and Jimmy Pineapple. Kinison began his career in Houston, Texas, where he performed in small clubs. After he and his first wife were divorced, he abandoned preaching and took up comedy as a profession. His brother Bill, however, noted that "ironically, he had no stage presence" and he was not very successful at making money from preaching. He preached from the age of 17 to 24 and recordings of his sermons reveal that he used a "fire and brimstone" style, punctuated with shouts similar to the ones he would later use in his stand-up routines. His mother married another preacher and moved to Tulsa, Oklahoma, where Kinison lived for a while. Kinison attended Pinecrest Bible Training Center in Salisbury Center, New York. He and his brothers emulated their father by becoming Pentecostal preachers. Sam later attended East Peoria Community High School in East Peoria.

Bill described this as the root of much of Sam's anger. His parents divorced when he was 11 and his brother Bill went to live with his father while Sam stayed with the rest of his family against his protestations. Kinison had two older brothers, Richard and Bill, and a younger brother, Kevin. His father pastored several churches around the country, receiving little income. The family moved to East Peoria, Illinois when Kinison was three months old. Samuel Burl Kinison was born in Yakima, Washington on December 8, 1953, the son of Marie Florence ( née Morrow) and Samuel Earl Kinison, a Pentecostal preacher.
